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Gene Expression Literature Summary
Assay
Age
In situ RNA (whole mount)
14.5 DPC

17 matching records from 17 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Stra8  stimulated by retinoic acid gene 8  
Results  Reference
1J:130928 Bagheri-Fam S, Sim H, Bernard P, Jayakody I, Taketo MM, Scherer G, Harley VR, Loss of Fgfr2 leads to partial XY sex reversal. Dev Biol. 2008 Feb 1;314(1):71-83
1J:108333 Bowles J, Knight D, Smith C, Wilhelm D, Richman J, Mamiya S, Yashiro K, Chawengsaksophak K, Wilson MJ, Rossant J, Hamada H, Koopman P, Retinoid signaling determines germ cell fate in mice. Science. 2006 Apr 28;312(5773):596-600
1J:179634 Chassot AA, Gregoire EP, Lavery R, Taketo MM, de Rooij DG, Adams IR, Chaboissier MC, RSPO1/beta-catenin signaling pathway regulates oogonia differentiation and entry into meiosis in the mouse fetal ovary. PLoS One. 2011;6(10):e25641
1J:262492 Harris A, Siggers P, Corrochano S, Warr N, Sagar D, Grimes DT, Suzuki M, Burdine RD, Cong F, Koo BK, Clevers H, Stevant I, Nef S, Wells S, Brauner R, Ben Rhouma B, Belguith N, Eozenou C, Bignon-Topalovic J, Bashamboo A, McElreavey K, Greenfield A, ZNRF3 functions in mammalian sex determination by inhibiting canonical WNT signaling. Proc Natl Acad Sci U S A. 2018 May 22;115(21):5474-5479
1*J:107319 Koubova J, Menke DB, Zhou Q, Capel B, Griswold MD, Page DC, Retinoic acid regulates sex-specific timing of meiotic initiation in mice. Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2474-9
1*J:222363 Kumar S, Chatzi C, Brade T, Cunningham TJ, Zhao X, Duester G, Sex-specific timing of meiotic initiation is regulated by Cyp26b1 independent of retinoic acid signalling. Nat Commun. 2011 Jan 11;2:151
1J:142245 Lin Y, Gill ME, Koubova J, Page DC, Germ cell-intrinsic and -extrinsic factors govern meiotic initiation in mouse embryos. Science. 2008 Dec 12;322(5908):1685-7
1J:326297 Livermore C, Simon M, Reeves R, Stevant I, Nef S, Pope M, Mallon AM, Wells S, Warr N, Greenfield A, Protection Against XY Gonadal Sex Reversal by a Variant Region on Mouse Chromosome 13. Genetics. 2020 Feb;214(2):467-477
1*J:283272 Livermore C, Warr N, Chalon N, Siggers P, Mianne J, Codner G, Teboul L, Wells S, Greenfield A, Male mice lacking ADAMTS-16 are fertile but exhibit testes of reduced weight. Sci Rep. 2019 Nov 20;9(1):17195
1*J:86170 Menke DB, Koubova J, Page DC, Sexual differentiation of germ cells in XX mouse gonads occurs in an anterior-to-posterior wave. Dev Biol. 2003 Oct 15;262(2):303-12
1J:158526 Naillat F, Prunskaite-Hyyrylainen R, Pietila I, Sormunen R, Jokela T, Shan J, Vainio SJ, Wnt4/5a signalling coordinates cell adhesion and entry into meiosis during presumptive ovarian follicle development. Hum Mol Genet. 2010 Apr 15;19(8):1539-50
1J:216825 Siggers P, Carre GA, Bogani D, Warr N, Wells S, Hilton H, Esapa C, Hajihosseini MK, Greenfield A, A novel mouse Fgfr2 mutant, hobbyhorse (hob), exhibits complete XY gonadal sex reversal. PLoS One. 2014;9(6):e100447
1J:172351 Warr N, Bogani D, Siggers P, Brixey R, Tateossian H, Dopplapudi A, Wells S, Cheeseman M, Xia Y, Ostrer H, Greenfield A, Minor Abnormalities of Testis Development in Mice Lacking the Gene Encoding the MAPK Signalling Component, MAP3K1. PLoS One. 2011;6(5):e19572
1J:191096 Warr N, Carre GA, Siggers P, Faleato JV, Brixey R, Pope M, Bogani D, Childers M, Wells S, Scudamore CL, Tedesco M, del Barco Barrantes I, Nebreda AR, Trainor PA, Greenfield A, Gadd45gamma and Map3k4 interactions regulate mouse testis determination via p38 MAPK-mediated control of Sry expression. Dev Cell. 2012 Nov 13;23(5):1020-31
1J:210362 Warr N, Siggers P, Carre GA, Bogani D, Brixey R, Akiyoshi M, Tachibana M, Teboul L, Wells S, Sanderson J, Greenfield A, Transgenic expression of Map3k4 rescues T-associated sex reversal (Tas) in mice. Hum Mol Genet. 2014 Jun 1;23(11):3035-44
1J:236335 Warr N, Siggers P, Carre GA, Wells S, Greenfield A, Genetic Analyses Reveal Functions for MAP2K3 and MAP2K6 in Mouse Testis Determination. Biol Reprod. 2016 May;94(5):103
1J:325977 Warr N, Siggers P, May J, Chalon N, Pope M, Wells S, Chaboissier MC, Greenfield A, Gadd45g is required for timely Sry expression independently of RSPO1 activity. Reproduction. 2022 Apr 22;163(6):333-340

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory